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PF-4708671

PF-4708671

Cat no: 019325

Supplier: United States Biological
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PF-4708671 is a highly specific inhibitor of p70 ribosomal S6 kinase (S6K1). PF-4708671 inhibits S6K1-mediated phosphorylation of S6 protein in response to IGF-1 (insulin-like growth factor 1), while having no effect on highly related RSK (p90 ribosomal S6 kinase) and MSK (mitogen- and stress-activated kinase) kinases. Form: Pale purple Solid Melting Point: 189-191 degrees C Solubility: DMSO, Methanol Pfizer Compound
Catalogue number: 019325
Size: 10mg
Form: Pale purple Solid
Alternative names: 2-[[4-(5-ethyl-4-pyrimidinyl)-1-piperazinyl]methyl]-6-(trifluoromethyl)-1H-benzimidazole; PF 4708671;
References: Pearce, L.R. et al.: Biochem. J., 431, 245 (2010);

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