PFDN5, ID (PFDN5, MM1, PFD5, Prefoldin subunit 5, C-Myc-binding protein Mm-1, Myc modulator 1)

This gene encodes a member of the prefoldin alpha subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. The encoded protein may also repress the transcriptional activity of the proto-oncogene c-Myc. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq].\n\nApplications:\nSuitable for use in Western Blot, Immunohistochemistry, ELISA\n\nRecommended Dilution:\nELISA: 1:1,000\nWestern Blot: 1:100-500\nImmunohistochemistry: 1:10-50\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

039900

Size

200ul

Applications

ELISA, IHC, WB

Hosts

Rabbit

Reactivities

Hum, Mouse

Form

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

P Type

Pab

Purity

Purified by Protein A affinity chromatography.

Isotype

IgG

References

Ma, H.C., et al. J. Biomed. Sci. 15(4):417-425(2008)\nYoshida, T., et al. Exp. Cell Res. 314(6):1217-1228(2008)\nLubyova, B., et al. J. Biol. Chem. 282(44):31944-31953(2007)\nHagio, Y., et al. J. Cell. Biochem. 97(1):145-155(2006)\nBruneel, A., et al. Proteomics 5(15):3876-3884(2005)

Additional Info

Human, mouse

Alternative Names

PFDN5, MM1, PFD5, Prefoldin subunit 5, C-Myc-binding protein Mm-1, Myc modulator 1