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PGLS Peptide

PGLS Peptide

Cat no: BS5852P

Supplier: Bioworld Technology, Inc.
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PGLS (6-phosphogluconolactonase), also known as 6PGL, is a 258 amino acid protein that belongs to the glucosamine/galactosamine-6-phosphate isomerase family and the 6-phosphogluconolactonase subfamily. Localizing to cytoplasm, PGLS is a particularly active enzyme that catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate, which is the second step of the pentose phosphate pathway. Highly conserved, PGLS shares 33% to 37% sequence similarity with yeast Sol1, Sol2, Sol3 and Sol4, 26% similarity with the C-terminal portion of human H6PD, 20% to 25% similarity with bacterial devB proteins and 17% similarity with human GNPDA1. PGLS erythrocyte deficiency, an autosomal dominant disorder, in conjunction with G6PD deficiency, may play a role in hemolytic anemia.
Catalogue number: BS5852P
Applications: Block/Neutralize/Inhibit
Swiss prot: O95336
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide PGLS. (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: 6-phosphogluconolactonase; 6PGL
Additional info: This peptide can be used with studies using BS5852 PGLS pAb.

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