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PHKG1 pAb

PHKG1 pAb

Cat no: BS5855


Supplier: Bioworld Technology, Inc.
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PHKG1 (phosphorylase kinase subunit (gamma)1), is a subunit of phosphorylase kinase (PHK) that belongs to the Ser/Thr protein kinase family. PHK is a hexadecameric protein composed of four (alpha) chains, four (beta) chains, four (gamma) chains and four (delta) chains. The (gamma) chains are catalytic chains, the (alpha) and (beta) chains are regulatory chains and the (delta) chains are calmodulins. PHKG1 contains two calmodulin-binding domains and one protein kinase domain. As the catalytic chain of PHK, PHKG1 is responsible for catalyzing the phosphorylation and activation of glycogen phosphorylase and therefore it plays an important role in the glycogenolytic pathway. Mutations in the gene encoding PHKG1 can lead to PHK deficiency and result in glycogen storage disease type 9C (GSD9C), also known as autosomal liver glycogenosis.
Catalogue number: BS5855
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Western Blot
Size: 100ug/100ul
Swiss prot: Q16816
Dilutions: WB: 1:500~1:1000 ICC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 293-338 of Human PHKG1.
Species: PHKG1 pAb detects endogenous levels of PHKG1 protein.
Molecular weight: ~ 45 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform; PHK-gamma-M; Phosphorylase kinase subunit gamma-1; Serine/threonine-protein kinase PHKG1; PHKG; PHK-(gamma)-M; PHK(gamma)-M; PHK-(gamma)M; PHK(gamma)M;
Additional info: For research use only, not for use in diagnostic procedure.

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