Phosphatase, Alkaline, Placental (PLAP, Alkaline Phosphatase Placental, Alkaline Phosphatase Placental Type, ALP, ALPP, Glycerophosphatase, PLAP-1, Regan Isozyme)

Placental alkaline phosphatase (PLAP) is a membrane bound, zinc-containing metalloenzyme synthesized by syncytiotrophoblast of placenta during the G1 phase of the cell cycle. PLAP is found only in higher primates, and it exhibits a high degree of genetic polymorphism. PLAP consists of 65kD subunit dimers that are heat resistant, whereas other alkaline phosphatase isoenzymes from liver, bone, kidney, and intestine are heat sensitive.\n\nApplications: \nSuitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.\n\nRecommended Dilution:\nImmunohistochemistry: Frozen and paraffin sections\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

P4071-16F

Size

100ug

Applications

ELISA, IHC, WB

Hosts

Mouse

Reactivities

Hum

Form

Supplied as a liquid in PBS, 15mM sodium azide, pH 7.4.

P Type

Mab

Purity

Purified (>95% SDS-PAGE)

Isotype

IgG2a

References

1. Travers P. and Bodmer W., Int. J. Cancer 33, 633 (1984) 2. Millan J. L. and Stigbrand T., Eur. J. Biochem. 136, 1 (1983) 3. Durbin H. et. al, Int. J. Cancer Suppl. 2, 50 (1988).

Additional Info

Recognizes throphoblast-derived membrane-associated enzyme from human alkaline phosphatase.