PI3K p110alpha (R519) Peptide

Cat no: BS3456P

Supplier: Bioworld Technology, Inc.

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Description
Additional Information

Phosphatidylinositol 3-kinase (PI 3-kinase) is composed of 85 kDa (p85) and 110 kDa (p110) subunits. p85 lacks PI 3-kinase activity and acts as an adapter, coupling p110 to activated protein tyrosine kinase. Two forms of p85 have been described (p85alpha and p85beta), each possessing one SH3 and two SH2 domains. Various p110 isoforms have been identified. p110alpha and p110beta interact with p85alpha, and p110alpha has also been shown to interact with p85beta in vitro. p110delta expression is restricted to white blood cells. It has been shown to bind p85alpha and beta, but it apparently does not phosphorylate these subunits. p110delta seems to have the capacity to autophosphorylate. p110gamma does not interact with the p85 subunits. It has been shown to be activated by alpha and betagamma heterotrimeric G proteins.

Catalogue number:	BS3456P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	P42336
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide PI3K p110alpha (R519). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	PIK3CA; MGC142161; MGC142163; PI3K; p110-alpha; Phosphatidylinositol-4; 5-bisphosphate 3-kinase catalytic subunit alpha isoform; Phosphatidylinositol-4; 5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha
Additional info:	This peptide can be used with studies using BS3456 PI3K p110alpha (R519) pAb.

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PI3K p110alpha (R519) Peptide

Cat no: BS3456P

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