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PI3K p85(alpha) pAb

PI3K p85(alpha) pAb

Cat no: BS6291


Supplier: Bioworld Technology, Inc.
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Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling.
Catalogue number: BS6291
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: P27986
Dilutions: WB: 1:500~1:2000 IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Recombinant full length Human PI3K p85(alpha).
Species: PI3K p85(alpha) pAb detects endogenous levels of PI3K p85(alpha) protein.
Molecular weight: ~ 85 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: GRB 1; GRB1; p85 alpha; p85; p85a; P85A; Phosphatidylinositol 3 kinase associated p 85 alpha; Phosphatidylinositol 3 kinase associated p85 alpha; Phosphatidylinositol 3 kinase regulatory 1; Phosphatidylinositol 3 kinase regulatory alpha subunit; Phosphatidylinositol 3 kinase regulatory subunit alpha; Phosphatidylinositol 3 kinase regulatory subunit polypeptide 1; Phosphatidylinositol 3 kinase; regulatory subunit; polypeptide 1 (p85 alpha); Phosphatidylinositol 3-kinase 85 a regulatory sub
Additional info: For research use only, not for use in diagnostic procedure.

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