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Pim-1 (I302) pAb

Cat no: BS2988

Pim-1 (I302) pAb

Pim-1 is a serine/threonine kinase that cooperates with c-Myc in lymphoid cell transformation. The expression of Pim-1 increases during the progression from early to late G1, remaining high at the G1/S boundary and G2 phases of the cell cycle. Pim-1 is regulated at both the transcriptional and translational level, and it has been shown to be induced by IL-2 stimulation. Pim-1 also plays a role in T cell differentiation, and it has been shown to stimulate c-Myc-mediated apoptosis upstream of caspase-3-like proteases.

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SPECIFICATIONS

Catalog Number

BS2988

Size

100ug/100ul

Applications

WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Form

liquid

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Antigen

Synthetic peptide, corresponding to amino acids 271-320 of Human Pim-1.

Species

Pim-1 (I302) pAb detects endogenous levels of Pim-1 protein .

Dilutions

WB: 1:500~1:1000

Swiss Prot

P06803

Storage Temp

Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.

Concentration

1ug/ul

Storage Buffer

1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Additional Info

For research use only, not for use in diagnostic procedure.

Molecular Weight

~ 50 kDa

Alternative Names

PIM1; EC 2.7.11.1; PIM

SUPPLIER INFO

Bioworld Technology, Inc.

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