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Pimprinine (5-(3-Indolyl)-2-methyloxazole, Antibiotic WS 30581C, Antibiotic APHE 3)

Pimprinine (5-(3-Indolyl)-2-methyloxazole, Antibiotic WS 30581C, Antibiotic APHE 3)

Cat no: P4186-68

Supplier: United States Biological
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Pimprinine is an indole alkaloid produced by many species of Streptomyces. Pimprinine is a potent inhibitor of monoamine oxidase and has shown antiepileptic effects. More recently, pimprinine showed promising anticonvulsant activity in electric seizure threshold tests in mice, comparable to phenyl hydantoin. Pimprinine also inhibited tremorine-induced tremors and analgesia in mice. Purity: >95% by HPLC Solubility: Soluble in ethanol, methanol, DMF or DMSO Related to: Indolmycin
Catalogue number: P4186-68
Size: 1mg
Purity: >95% by HPLC
Alternative names: 5-(3-Indolyl)-2-methyloxazole, Antibiotic WS 30581C, Antibiotic APHE 3
References: 1. Isolation, characterization and synthesis of pimprinine, pimprinethine and pimprinaphine, metabolites of Streptoverticillium olivoreticuli. Koyama Y. et al. Agri. Biol. Chem. 1981, 45, 1285. 2. Pimprinine, an extracellular alkaloid produced by Streptomyces CDRIL-312: fermentation, isolation and pharmacological activity. Naik S.R. et al. J. Biotechnol. 2001, 88, 1.

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