Cell-permeable. A thiazolidinedione (TZD) derivative that acts as a selective peroxisome proliferator-activated receptor gamma (PPARg) agonist (EC50 = 0.69uM). An antidiabetic agent; improves insulin sensitivity.
Molecular Weight:
~356.44
Solubility:
DMSO (>2mg/ml)
Storage and Stability:
Lyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.