PITPNB Peptide

Cat no: BS5858P

Supplier: Bioworld Technology, Inc.

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Description
Additional Information

The lipid binding proteins known as phosphatidylinositol transfer proteins (PITP) facilitate the formation of phosphatidylinositol derived second messenger molecules, which are related to the phospholipase C and phosphoinositide 3-kinase pathways. PITP are ubiquitously expressed proteins that transfer phosphatidylinositol (PI) and phosphatidylcholine (PC) between membranes enriched in PI or PC to membranes that are deficient in PI or PC. PITP mobilizes PI from the endoplasmic recticulum and regulates the release of PI from stored vesicles in the Golgi network. In mammalian cells, three smaller forms of soluble PITP are present, designated PITPalpha, PITPbeta and retinal degeneration B (rdgB) beta. PITPbeta is a 271 amino acid protein that is widely expressed in various tissues. Though required for Golgi targeting, constitutive phosphorylation of Ser-262 has no effect on phospholipid transfer activity. There are two isoforms of PITPbeta that are produced as a result of alternative splicing events.

Catalogue number:	BS5858P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	P48739
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide PITPNB. (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	Phosphatidylinositol transfer protein beta isoform; PI-TP-beta; PtdIns transfer protein beta; PtdInsTP beta; PITPbeta; PI-TPbeta; PI-TP-beta
Additional info:	This peptide can be used with studies using BS5858 PITPNB pAb.

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PITPNB Peptide

Cat no: BS5858P

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