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PKC 0 (G532) Peptide

PKC 0 (G532) Peptide

Cat no: AP0410P


Supplier: Bioworld Technology, Inc.
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Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into at least two major classes including conventional (c) PKC isoforms (alpha, betaI, betaII and gamma ) and novel (n) PKC isoforms (delta, E, ?, ? and 0). Patterns of expression for each PKC isoform differs among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of nPKC delta and E are independent of Ca2+. On the other hand, nPKC delta and E, as well as all of the cPKC members, possess phorbol ester-binding activities and kinase activities.
Catalogue number: AP0410P
Applications: Block/Neutralize/Inhibit
Swiss prot: Q04759
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide PKC 0 (G532). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Protein kinase C theta type; nPKC-theta; PRKCQ; PRKCT
Additional info: This peptide can be used with studies using AP0410 PKC 0 (G532) pAb.

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