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PKC ? (P556) Peptide

PKC ? (P556) Peptide

Cat no: BS1579P


Supplier: Bioworld Technology, Inc.
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Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into at least two major classes including conventional (c) PKC isoforms (alpha, betaI, betaii and gamma ) and novel (n) PKC isoforms (delta, E , ?, ? and 0). Patterns of expression for each PKC isoform differs among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of nPKC delta and E are independent of Ca++. On the other hand, nPKC delta and E, as well as all of the cPKC members, possess phorbol ester-binding activities and kinase activities
Catalogue number: BS1579P
Applications: Block/Neutralize/Inhibit
Swiss prot: Q05513
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide PKC ? (P556). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Protein kinase C zeta type; nPKC-zeta; PRKCZ; PKC2; PKC zeta
Additional info: This peptide can be used with studies using BS1579 PKC ? (P556) pAb.

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