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PKD1/2/3 (I740) pAb

PKD1/2/3 (I740) pAb

Cat no: BS1685

Supplier: Bioworld Technology, Inc.
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Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into at least two major classes including conventional (c) PKC isoforms ((alpha), (beta)I, (beta)II and (gamma)) and novel (n) PKC isoforms ((delta), E, ?, n and 0). Patterns of expression for each PKC isoform differs among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of nPKC (delta) and E are independent of Ca 2+. On the other hand, nPKC (delta) and E, as well as all of the cPKC members, possess phorbol ester-binding activities and kinase activities.
Catalogue number: BS1685
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Western Blot
Size: 100ug/100ul
Swiss prot: Q15139/Q9BZL6/O94806
Dilutions: WB: 1:500~1:1000
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 708-763 of Human PKD1.
Species: PKD1/2/3 (I740) pAb detects endogenous levels of PKD1/2/3 protein.
Molecular weight: ~ 90 to 140 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Serine/threonine-protein kinase D1; Protein kinase C mu type; Protein kinase D; nPKC-D1; nPKC-mu; PRKD1; PKD; PKD1; PRKCM; PKCmicro; PKC micro; PKC-micro; Serine/threonine-protein kinase D2; nPKC-D2; PRKD2; PKD2; HSPC187; PKC mu; PKCmu; Serine/threonine-protein kinase D3; Protein kinase C nu type; Protein kinase EPK2; nPKC-nu; PRKD3; EPK2; PRKCN; PKD3; PKC?; PKC ?; PKC-?; PKC nu; PKCnu; PKC-nu
Additional info: For research use only, not for use in diagnostic procedure.

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