PKM2 (K230) Peptide

The PKM2 (pyruvate kinase, muscle) gene encodes the M1- and M2-type isoenzymes through alternative splicing events. Both M1- and M2-type isoforms exists as tetramers and are stimulated by fructose 1,6-bisphosphate. In addition, both isoforms exhibit thyroid hormone binding activity and may be referred to as CTHBP (cytosolic thyroid hormone-binding protein) or THBP1. The M2-type isoform also interacts with Oct-4 via its C-terminal domain, functioning to enhance Oct-4 transcriptional activity.

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SPECIFICATIONS

Catalog Number

BS9041P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide PKM2 (K230). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

P14618

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS9041 PKM2 (K230) pAb.

Alternative Names

CTHBP; \nCytosolic thyroid hormone binding protein; \nCytosolic thyroid hormone-binding protein; \nKPYM; \nMGC3932; \nOIP 3; \nOIP-3; \nOip3; \nOIP3; \nOPA interacting protein 3; \nOpa-interacting protein 3; \np58; \nPK Muscle type; \nPK; muscle type; \nPK2; \nPk3; \nPKM; \nPKM2; \nPYKM; \nPyruvate kinase 2/3; \nPyruvate kinase isozymes M1/M2; \nPyruvate kinase muscle; \nPyruvate kinase muscle isozyme; \nTCB; \nTHBP1; \nThyroid hormone binding protein 1; \nThyroid hormone binding protein cytosolic; \nThyroid hormone