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PKM2 (M2PK, Pyruvate Kinase Isozymes M1/M2, Cytosolic Thyroid Hormone-binding Protein, CTHBP, Opa-interacting Protein 3, OIP-3, Pyruvate Kinase 2/3, Pyruvate Kinase Muscle Isozyme, Thyroid Hormone-binding Protein 1, THBP1, Tumor M2-PK, p58, OIP3, PK2, PK3

Cat no: P9545-32B

PKM2 (M2PK, Pyruvate Kinase Isozymes M1/M2, Cytosolic Thyroid Hormone-binding Protein, CTHBP, Opa-interacting Protein 3, OIP-3, Pyruvate Kinase 2/3, Pyruvate Kinase Muscle Isozyme, Thyroid Hormone-binding Protein 1, THBP1, Tumor M2-PK, p58, OIP3, PK2, PK3

Pyruvate kinase is a key enzyme in the glycolytic pathway. The M2 isoenzyme of pyruvate kinase is specifically expressed at high levels in tumor cells, and can be measured in plasma of patients with advanced breast cancer. The marker is useful for measuring disease activity, sensitivity to chemotherapy and recurrence.\n\nApplications:\nSuitable for use in ELISA, Western Blot, Dot Blot, Immunohistochemistry, Immunoassays, development of rapid tests and other antibody recognition assays. Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

P9545-32B

Size

100ul

Applications

ELISA, IHC, WB

Hosts

Sheep

Form

Supplied as a liquid in 20mM phosphate, 150mM sodium chloride, pH 7.2, 0.09% sodium azide.

P Type

Pab

Purity

Purified by immunoaffinity chromatography.

Isotype

IgG

References

1. Luftner D. et al. (2000) Anticancer Res. 20(6D): 5077-82.

Additional Info

Recognizes human M2PK.

Read more on Supplier website

Applications

ELISA

Reactivities

Hum

More info

Applications

IF

Hosts

Mouse

More info

Applications

ELISA, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, IHC, WB

Hosts

Mouse

More info

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum

More info

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

More info
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