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PLK1 (D204) Peptide

PLK1 (D204) Peptide

Cat no: BS1687P


Supplier: Bioworld Technology, Inc.
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PLK1 (polo-like kinase 1) is a member of the serine/threonine protein kinase family, cdc5/polo subfamily. PLK1 contains two polo box domains with a predicted molecular weight of 68 kDa. PLK1 has been shown to regulate cdc2/cyclin B through phosphorylation and activation of cdc25c phosphatase. PLK1 is modified by phosphorylation at Threonine 210. PLK1 may also be required for cell division. Depletion of PLK1 results in apoptosis and deregulation of expression of PKL1 is correlated with development of many malignancies. Studies have shown that ab14209 preferentially detects the kinetochore-associated pool of Plk1. An alternative antibody, Mouse monoclonal to Plk1 (ab14210) preferentially stains centrosomal-associated Plk1.
Catalogue number: BS1687P
Applications: Block/Neutralize/Inhibit
Swiss prot: P53350
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide PLK1 (D204). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: PLK1; EC 2.7.11.21; PLK; PLK-1; STPK13
Additional info: This peptide can be used with studies using BS1687 PLK1 (D204) pAb.

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