Home  >  Products  >  PLK4 (Serine/threonine-protein Kinase PLK4, Polo-like Kinase 4, PLK-4, Serine/Threonine-protein Kinase 18, Serine/Threonine-protein Kinase Sak, SAK, STK18)
PLK4 (Serine/threonine-protein Kinase PLK4, Polo-like Kinase 4, PLK-4, Serine/Threonine-protein Kinase 18, Serine/Threonine-protein Kinase Sak, SAK, STK18)

PLK4 (Serine/threonine-protein Kinase PLK4, Polo-like Kinase 4, PLK-4, Serine/Threonine-protein Kinase 18, Serine/Threonine-protein Kinase Sak, SAK, STK18)

Cat no: P4275-15E

Supplier: United States Biological
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SAK is involved in regulation of cell cycle. SAK is a key regulator of centriole duplication. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:32,000 Western Blot: 1-3ug/ml, observed in Human Colon lysates on ~110kD bands Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: P4275-15E
Reactivities: Human, Bovine, Canine
Hosts: Goat
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
References: 1. Martindill DM, Risebro CA, Smart N, Franco-Viseras Mdel M, Rosario CO, Swallow CJ, Dennis JW, Riley PR. Nucleolar release of Hand1 acts as a molecular switch to determine cell fate. Nat Cell Biol. 2007 Oct;9(10):1131-41. 2. Syed N, Smith P, Sullivan A, Spender LC, Dyer M, Karran L, O'Nions J, Allday M, Hoffmann I, Crawford D, Griffin B, Farrell PJ, Crook T. Transcriptional silencing of Polo-like kinase 2 (SNK/PLK2) is a frequent event in B-cell malignancies. Blood. 2006 Jan 1;107(1):250-6. Epub 2005 Sep 13.
Additional info: Recognizes human PLK4. Species sequence homology: Bovine and canine.

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