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Polyquaternium 1

Cat no: 019858


Supplier: United States Biological
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Polyquaternium 1 is an antimicrobial preservative used for rabbit ocular surface study on polyquad-preserved travoprost/timolol, benzalkonium chloride-preserved travoprost/timolol, and latanoprost/timolol in fixed combinations. Melting Point: >210 degrees C (decomposes) Atmosphere: Inert gas Solubility: Methanol, Water Method for Determinng Identity: Proton NMR (D2O) Spectroscopic Analysis and Mass Spectrometric Analysis Elemental Analysis: As Reported Sample values: 47.39% C, 9.66% H, 8.71% N, 21.1% Cl Storage and Stability: Store at 4 degrees C. Caution: Hygroscopic; store under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.
Catalogue number: 019858
Size: 500mg
Form: Light brown to brown solid
Purity: ~95%
Alternative names: a-[4-[Tris(2-hydroxyethyl)ammonio]-2-buten-1-yl]-Omega-[tris(2-hydroxyethyl)ammonio]poly[(dimethyliminio)-2-butene-1,4-diyl Chloride] Chloride Onamer M; Onyxsperse 12S; Polidronium Chloride; Polyquad; Polyquat 1
References: 1. Pisella, P., et al.: Br. J. Ophthalmol., 86, 418 (2002). 2. Robin, A., et al.: Am. J. Ophthalmol., 144, 533 (2007). 3. Schmier, J., et al.: Curr. Med. Res. Opin., 23, 2867 (2007)

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