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Polysialic Acid NCAM (PSA-NCAM)

Cat no: P4460

Polysialic Acid NCAM (PSA-NCAM)

Polysialic acid (PSA) is a long, linear homopolymer that is attached to the neural cell adhesion molecule (NCAM). It has the remarkable ability to down-regulate a wide variety of contact-dependent cell interactions. This activity is believed to stem from the ability of the charged polymer to occupy a large hydrated volume and thereby cause a direct physical hindrance of cell

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SPECIFICATIONS

Catalog Number

P4460

Size

50ul

Applications

ICC, IHC, WB

Hosts

Mouse

Reactivities

Mouse

Form

Supplied as a liquid in 50% glycerol. No preservatives added.

P Type

Mab

Purity

Ascites

Isotype

IgM

References

1. Koizumi, Hiroyuki, et al., Nat Neurosci. 9: 779-786 (2006). 2. Ramirez-Castillejo, C., et al., Nature Neurosci. 9: 331-339 (2006). 3. Ng, K.L., et al., Science 308: 1923-1927 (2005). 4. Scheffler, B., et al., Proc. Nat. Acad. Sci. USA 102(26): 9353-9358 (2005). 5. Medrano, S., et al., Neurobiol. Aging 30: 483-497 (2009).

Additional Info

Recognizes mouse Polysialic Acid NCAM at 150-300kD. Works well on all vertebrate species expressing PSA-NCAM.

Read more on Supplier website

Applications

ELISA

Reactivities

Hum

More info

Applications

IF

Hosts

Mouse

More info

Applications

ELISA, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, IHC, WB

Hosts

Mouse

More info

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum

More info

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

More info
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