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Postsynaptic Density Protein 95 (PSD-95, PSD95, Discs Large Homolog 4, DLG4, Human Post-synaptic Density Protein 95, Synapse-associated Protein 90, SAP90, SAP-90)

Cat no: P4700-12

Postsynaptic Density Protein 95 (PSD-95, PSD95, Discs Large Homolog 4, DLG4, Human Post-synaptic Density Protein 95, Synapse-associated Protein 90, SAP90, SAP-90)

Postsynaptic Density protein 95 (PSD95) belongs to the membrane-associated guanylate kinase (MAGUK) family. As a scaffolding protein, PSD95 controls of receptor trafficking during synaptic plasticity by anchoring synaptic proteins. Specifically, PSD95 is necessary in synaptic plasticity associated with NMDA receptor signaling. After hetermultimerization with DLG2, PSD95 associates with cytoplasmic tail of NMDA receptor subunit and potassium channel clusters. PSD95 has been linked to autism, drug addiction, and learning\n\nApplications:\nSuitable for use in Flow Cytometry, ELISA, Western Blot, Immunoprecipitation and Immunocytochemistry. Other applications not tested.\n\nRecommended Dilutions:\nWestern Blot: 1:1000-1:5000\nImmunocytochemistry: 1:100-1:250\nFlow Cytometry: 1:20\nImmunoprecipitation: 1:10\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.\n\nManufactured incorporating RabMAb(R) technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.

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SPECIFICATIONS

Catalog Number

P4700-12

Size

100ul

Applications

ELISA, FC, ICC, IP, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Form

Supplied as a liquid in PBS, pH 7.4, 0.05% BSA, 0.01% sodium azide, 50% glycerol

P Type

Mab

Purity

Supernatant

Isotype

IgG

References

1.El-Husseini AE. et al. Science 17:1364-1368

Additional Info

Recognizes human PSD95. Species Crossreactivity: mouse and rat

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SUPPLIER INFO

Applications

ELISA

Reactivities

Hum

More info

Applications

IF

Hosts

Mouse

More info

Applications

ELISA, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, IHC, WB

Hosts

Mouse

More info

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum

More info

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

More info

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