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PPA1 (Inorganic Pyrophosphatase 1, IOPPP, IPP1, PP1, PPase)

Cat no: 145577

PPA1 (Inorganic Pyrophosphatase 1, IOPPP, IPP1, PP1, PPase)

PPA1 (Inorganic pyrophosphatase 1; also PPase and IOPPP) is a 32-36kD cytoplasmic member of the PPase family of enzymes. It is ubiquitously expressed, and acts on di- (or pyro) phosphate, generating orthophosphate in a Mg+-dependent manner. This activity can both generate energy for cells, or in the case of osteoblasts, provide raw material for calcification. The consumption of pyrophosphate may also remove inhibitors of enzymes such as guanylyl cyclase, and PPA1 itself is also reported to stimulate gene expression. Human PPA1 is 289 amino acids (aa) in length. There is one pyrophosphatase domain between aa42-255, and two utilized acetylation sites at aa57 and aa228. PPA1 is known to form homodimers. There is one potential alternative start site at aa46. Full

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SPECIFICATIONS

Catalog Number

145577

Size

100ug

Applications

ELISA, WB

Hosts

Mouse

Reactivities

Hum, Mouse, Rat

Form

Supplied as a lyophilized powder in PBS, Trehalose. Reconstitute with sterile PBS.

P Type

Mab

Purity

Purified by Protein A or G affinity chromatography.

Isotype

IgG2b

Additional Info

Recognizes human Inorganic Pyrophosphatase/PPA1 in direct ELISAs and human, mouse, and rat Inorganic Pyrophosphatase/PPA1 in Western blots.

Read more on Supplier website

Applications

ELISA

Reactivities

Hum

More info

Applications

IF

Hosts

Mouse

More info

Applications

ELISA, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, IHC, WB

Hosts

Mouse

More info

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum

More info

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

More info
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