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PPP2R2A pAb

Cat no: BS6928

PPP2R2A pAb

Protein phosphatase 2A subunit B isoform R2-(alpha) (PPP2R2A) is the component of regulatory subunit B of serine/threonine protein phosphatase 2A (PP2A). PPP2R2A belongs to the R2/B55/PR55 family of regulatory subunit B. Evidence suggests that subunit PPP2R2A enhances TGF-(beta), Activin, and Nodal signaling pathways and may play an important role in cell cycle regulation . PPP2R2A/PP2A, B55-(alpha)/PR55-(alpha) isoform interacts with the type I TGF-(beta) receptors via unique WD-40 repeats that contribute to the anti-proliferative function of TGF-(beta) receptors.

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SPECIFICATIONS

Catalog Number

BS6928

Size

100ug/100ul

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Form

liquid

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Antigen

Recombinant full length Human PPP2R2A.

Species

PPP2R2A pAb detects endogenous levels of PPP2R2A protein.

Dilutions

WB: 1:500~1:2000\nIHC: 1:50~1:200

Swiss Prot

P63151

Storage Temp

Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.

Concentration

1ug/ul

Storage Buffer

1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Additional Info

For research use only, not for use in diagnostic procedure.

Molecular Weight

~ 55 kDa

Alternative Names

B55-ALPHA; B55A; FLJ26613; MGC52248; PR52A; PR55A;

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