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PPP2R5A pAb

PPP2R5A pAb

Cat no: BS5863


Supplier: Bioworld Technology, Inc.
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In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. Four major families of protein phosphatase catalytic subunits have been identified, designated PP1, PP2A, PP2B (calcineurin) and PP2C. An additional protein phosphatase catalytic subunit, PPX (also known as PP4) is a putative member of a novel PP family. The PP2A family comprises subfamily members PP2A(alpha) and PP2A(beta). The PP2A catalytic subunit associates with a variety of regulatory subunits. Regulatory subunits include PP2A-A-(alpha) and -A-(beta), PP2A-B-(alpha) and -B-(beta), PP2A-C-(alpha) and -C-(beta), PP2A-B56-(alpha), -B56-(beta), -B56-(gamma) and -B56-(delta).
Catalogue number: BS5863
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Western Blot
Size: 100ug/100ul
Swiss prot: Q15172
Dilutions: WB: 1:500~1:1000 ICC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 363-408 of Human PPP2R5A.
Species: PPP2R5A pAb detects endogenous levels of PPP2R5A protein.
Molecular weight: ~ 56 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform; PP2A B subunit isoform B'-alpha; PP2A B subunit isoform B56-alpha; PP2A B subunit isoform PR61-alpha; PR61alpha; PP2A B subunit isoform R5-alpha; PP2A-B56-(alpha); PP2A-B56(alpha); PP2A B56-(alpha); PP2AB56(alpha); PR61(alpha); PP2A-B-PR61(alpha)
Additional info: For research use only, not for use in diagnostic procedure.

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