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PRAF2 (L166) Peptide

Cat no: BS1195P

PRAF2 (L166) Peptide

JM4 (Jena-Muenchen 4), also known as PRAF2 (PRA1 domain family, member 2), is a 178 amino acid endosomal multi-pass membrane protein involved in vesicular trafficking and Endoplasmic reticulum/Golgi transport. As a member of the PRA1 family, JM4 contains four putative transmembrane (TM) domains, interacts with the CC chemokine receptor 5 (CCR5) and colocalizes with Calnexin in the ER and mannose 6-phosphate receptor (CD-MPR) in the Golgi apparatus. While ubiquitously expressed, JM4 has been found at high levels in small intestine, lung, pancreas, spleen, Purkinje cells of the cerebellum and in neuronal cells of the hippocampus, cerebral cortex and lateral ventricles of the brain. JM4 plays a proapoptic role in cerulenin-induced neuroblastoma apoptosis and has been implicated in human cancer.

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SPECIFICATIONS

Catalog Number

BS1195P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide PRAF2 (L166). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

O60831

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS1195 PRAF2 (L166) pAb.

Alternative Names

PRAF2; JM4; PRA1 family protein 2;

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