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PREP (PE, Prolyl Endopeptidase, Post-proline Cleaving Enzyme, PEP)

PREP (PE, Prolyl Endopeptidase, Post-proline Cleaving Enzyme, PEP)

Cat no: P9017-85C

Supplier: United States Biological
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Prolyl Endopeptidase is a cytosolic prolyl endopeptidase which cleaves peptide bonds on the C-terminal side of prolyl residues within peptides that are up to approximately 30aa long. Prolyl endopeptidases have been reported to be involved in the maturation and degradation of peptide hormones and neuropeptides. Applications: Suitable for use in ELISA and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:16,000 Immunohistochemistry (Paraffin): 3-6ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: P9017-85C
Reactivities: Human, Mouse, Rat, Bovine, Canine, Porcine
Hosts: Goat
Applications: ELISA, Immunohistochemistry
Size: 100ug
Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
References: 1. Momeni N, Nordstrom BM, Horstmann V, Avarsaji H, Sivberg BV. Alterations of prolyl endopeptidase activity in the plasma of children with autistic spectrum disorders. BMC Psychiatry. 2005 Jun 2;5(1):27.
Additional info: Recognizes human PREP. Species sequence homology: Bovine, canine, mouse, porcine and rat.

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