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Prothrombin (G724) Peptide

Cat no: BS2552P

Prothrombin (G724) Peptide

Hemostasis following tissue injury involves the deployment of essential plasma procoagulants (Prothrombin and Factors X, IX, V and VIII), which mediate a blood coagulation cascade that leads to the formation of insoluble Fibrin clots and the promotion of platelet aggregation. Proteolytic cleavage of Prothrombin (Factor II) at residue 44 leads to formation of Thrombin in the first step of the coagulation cascade. Thrombin cleaves bonds between Arg and Gly and activates Factors V, VII, VIII and XIII in complex with thrombomodulin and Protein C. Thrombin maintains vascular integrity during development and postnatal life and coordinates connective tissue proteins by stimulating fibroblast procollagen production.

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SPECIFICATIONS

Catalog Number

BS2552P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide Prothrombin (G724). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

P00734

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS2552 Prothrombin (G724) pAb.

Alternative Names

Effector cell protease receptor 1; Coagulation factor II; F2\n

SUPPLIER INFO

Bioworld Technology, Inc.

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