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Prothrombin (G724) Peptide

Prothrombin (G724) Peptide

Cat no: BS2552P

Supplier: Bioworld Technology, Inc.
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Hemostasis following tissue injury involves the deployment of essential plasma procoagulants (Prothrombin and Factors X, IX, V and VIII), which mediate a blood coagulation cascade that leads to the formation of insoluble Fibrin clots and the promotion of platelet aggregation. Proteolytic cleavage of Prothrombin (Factor II) at residue 44 leads to formation of Thrombin in the first step of the coagulation cascade. Thrombin cleaves bonds between Arg and Gly and activates Factors V, VII, VIII and XIII in complex with thrombomodulin and Protein C. Thrombin maintains vascular integrity during development and postnatal life and coordinates connective tissue proteins by stimulating fibroblast procollagen production.
Catalogue number: BS2552P
Applications: Block/Neutralize/Inhibit
Swiss prot: P00734
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide Prothrombin (G724). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Effector cell protease receptor 1; Coagulation factor II; F2
Additional info: This peptide can be used with studies using BS2552 Prothrombin (G724) pAb.

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