Home  >  Products  >  PRPF31 (U4/U6 Small Nuclear Ribonucleoprotein Prp31, Pre-mRNA-Processing Factor 31, Serologically Defined Breast Cancer Antigen NY-BR-99, U4/U6 snRNP 61kD Protein, Protein 61K, hPrp31, PRP31)
PRPF31 (U4/U6 Small Nuclear Ribonucleoprotein Prp31, Pre-mRNA-Processing Factor 31, Serologically Defined Breast Cancer Antigen NY-BR-99, U4/U6 snRNP 61kD Protein, Protein 61K, hPrp31, PRP31)

PRPF31 (U4/U6 Small Nuclear Ribonucleoprotein Prp31, Pre-mRNA-Processing Factor 31, Serologically Defined Breast Cancer Antigen NY-BR-99, U4/U6 snRNP 61kD Protein, Protein 61K, hPrp31, PRP31)

Cat no: P9121-40B

Supplier: United States Biological
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Involved in pre-mRNA splicing. Required for U4/U6.U5 tri-snRNP formation. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:16,000 Western Blot: 0.3-1ug/ml, lysates of cell line A431 observed on ~60kD bands Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: P9121-40B
Reactivities: Human, Canine
Hosts: Goat
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
References: 1. Makarova OV, Makarov EM, Liu S, Vornlocher HP, Luhrmann R. Protein 61K, encoded by a gene (PRPF31) linked to autosomal dominant retinitis pigmentosa, is required for U4/U6*U5 tri-snRNP formation and pre-mRNA splicing. EMBO J. 2002 Mar 1;21(5):1148-57.
Additional info: Recognizes human RP11. Species sequence homology: Canine.

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