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PSMA3 pAb

PSMA3 pAb

Cat no: BS6287

Supplier: Bioworld Technology, Inc.
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The 20S proteasome is the major proteolytic enzyme complex involved in intracellular protein degradation. It consists of four stacked rings, each with seven distinct subunits. The two outer layers are identical rings composed of (alpha) subunits (called PSMAs), and the two inner layers are identical rings composed of (beta) subunits. While the catalytic sites are located on the (beta) rings, the (alpha) subunits are important for assembly and as binding sites for regulatory proteins. Seven different (alpha) and ten different (beta) proteasome genes have been identified in mammals. PA700, PA28, and PA200 are three major protein complexes that function as activators of the 20S proteasome. PA700 binds polyubiquitin with high affinity and associates with the 20S proteasome to form the 26S proteasome, which preferentially degrades poly-ubiquitinated proteins ).
Catalogue number: BS6287
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: P25788
Dilutions: WB: 1:500~1:2000 IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Recombinant full length Human PSMA3.
Species: PSMA3 pAb detects endogenous levels of PSMA3 protein.
Molecular weight: ~ 28 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: HC8; Macropain subunit C8; MGC12306; MGC32631; Multicatalytic endopeptidase complex subunit C8; Proteasome (prosome macropain) subunit alpha type 3; Proteasome alpha 3 subunit; Proteasome component C8; Proteasome subunit alpha type 3; Proteasome subunit alpha type-3; Proteasome subunit C8; PSA3; PSC3; PSMA3;
Additional info: For research use only, not for use in diagnostic procedure.

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