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PSME3 mAb

PSME3 mAb

Cat no: MB0010


Supplier: Bioworld Technology, Inc.
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Subunit of the 11S REG-gamma (also called PA28-gamma) proteasome regulator, a donut-shaped homoheptamer which associates with the proteasome. 11S REG-gamma activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. Facilitates the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. May also be involved in cell cycle regulation.
Catalogue number: MB0010
Reactivities: Human
Hosts: Mouse
Applications: Western Blot
Size: 100ug/100ul
Swiss prot: P61289
Dilutions: WB: 1:1000
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Recombinant full length Human PSME3.
Species: This antibody detects endogenous levels of PSME3 and does not cross-react with related proteins
Molecular weight: Predicted band size:30KDa Observed band size:34Kda
Purity: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: PA28gamma; Ki antigen; Ki nuclear autoantigen; proteasome activator 28-gamma; 11S regulator complex gamma subunit 11S regulator complex subunit gamma; proteasome activator 28 subunit gamma activator of multicatalytic protease subunit 3
Additional info: For research use only, not for use in diagnostic procedure.

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