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PSMG2, Recombinant, Human, aa1-264, His-tag (Proteasome Assembly Chaperone 2, PAC-2, Hepatocellular Carcinoma-susceptibility Protein 3, Tumor Necrosis Factor Superfamily Member 5-induced Protein 1, HCCA3, PAC2, TNFSF5IP1)

Cat no: 029686

PSMG2, Recombinant, Human, aa1-264, His-tag (Proteasome Assembly Chaperone 2, PAC-2, Hepatocellular Carcinoma-susceptibility Protein 3, Tumor Necrosis Factor Superfamily Member 5-induced Protein 1, HCCA3, PAC2, TNFSF5IP1)

PSMG2, promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization.\n\nSource:\nRecombinant corresponding to aa1-264 from human PSMG2, fused to His-tag at N-terminal expressed in E.coli.\n\nAA Sequence:\nMGSSHHHHHH SSGLVPRGSH MGSMFVPCGE SAPDLAGFTL LMPAVSVGNV GQLAMDLIIS TLNMSKIGYF YTDCLVPMVG NNPYATTEGN STELSINAEV YSLPSRKLVA LQLRSIFIKY KSKPFCEKLL SWVKSSGCAR VIVLSSSHSY QRNDLQLRST PFRYLLTPSM QKSVQNKIKS LNWEEMEKSR CIPEIDDSEF CIRIPGGGIT KTLYDESCSK EIQMAVLLKF VSEGDNIPDA LGLVEYLNEW LQILKPLSDD PTVSASRWKI PSSWRLLFGS GLPPALF\n\nMolecular Weight:\n~31.8kD (MALDI-TOF)\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

029686

Size

50ug

Form

Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 40% glycerol, 0.1M sodium chloride.

Purity

~90% (SDS-PAGE)

References

1. Hirano Y., et al. (2005) Nature. 437:1381-1385 2. Le Tallec B., et al. (2007) Mol. Cell. 27:660-674

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