Home  >  Products  >  PTBP2 (Polypyrimidine Tract-binding Protein 2, Neural Polypyrimidine Tract-binding Protein, Neurally-enriched Homolog of PTB, PTB-like Protein, NPTB, PTB, PTBLP)
PTBP2 (Polypyrimidine Tract-binding Protein 2, Neural Polypyrimidine Tract-binding Protein, Neurally-enriched Homolog of PTB, PTB-like Protein, NPTB, PTB, PTBLP)

PTBP2 (Polypyrimidine Tract-binding Protein 2, Neural Polypyrimidine Tract-binding Protein, Neurally-enriched Homolog of PTB, PTB-like Protein, NPTB, PTB, PTBLP)

Cat no: P4453-10C

Supplier: United States Biological
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The protein encoded by this gene binds to the intronic cluster of RNA regulatory elements, downstream control sequence (DCS). It is implicated in controlling the assembly of other splicing-regulatory proteins. This protein is very similar to the polypyrimidine tract binding protein but it is expressed primarily in the brain. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA: 1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: P4453-10C
Reactivities: Human, Mouse, Rat
Hosts: Goat
Applications: ELISA
Size: 100ug
Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
References: 1. Boutz PL, Stoilov P, Li Q, Lin CH, Chawla G, Ostrow K, Shiue L, Ares M Jr, Black DL. A post-transcriptional regulatory switch in polypyrimidine tract-binding proteins reprograms alternative splicing in developing neurons. Genes Dev. 2007 Jul 1;21(13):1636-52.
Additional info: Recognizes PTBP2. Species sequence homology: Human, mouse and rat.

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