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PTP1B (Y46) Peptide

Cat no: BS1589P

PTP1B (Y46) Peptide

The phosphorylation of proteins at tyrosine residues has long been recognized as an important regulatory component of signal transduction. This is areversible process, involving both enzymes that phosphorylate proteins ontyrosine residues as well as a rapidly expanding family of protein tyrosinephosphatases. These latter enzymes bear little resemblance to either theprotein serine and protein threonine phosphatases or to the acid and alkalinephosphatases. In most tissues, the major PTPase is a vanadate- and molybdate-sensitive protein of approximately 40 kDa molecular weight. On the basis of sequence analysis, PTP1B expressed in human placenta exhibits similarities both with the common leukocyte antigen (CD45) and with LAR, ahomolog of the neural adhesion molecule (NCAM). PTPase 1B is synthesized as a 435 amino acid precursor protein which is cleaved to generate the active 321 amino acid enzyme.

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SPECIFICATIONS

Catalog Number

BS1589P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide PTP1B (Y46). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

P18031

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS1589 PTP1B (Y46) pAb.

Alternative Names

PTPN1; EC 3.1.3.48; PTP-1B; PTP1B

SUPPLIER INFO

Bioworld Technology, Inc.

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