PTPa, NT (Receptor-type Tyrosine-protein Phosphatase alpha, Protein-tyrosine Phosphatase alpha, R-PTP-alpha, PTPRA, PTPRL2) (AP)

Phosphorylation of receptors by protein kinases is a process that can be reversed by a group of enzymes called protein phosphatases. Coordinated control of kinases and phosphatases provides the cell with the capacity to rapidly switch between phosphorylated and dephosphorylated protein states in dynamic response to environmental stimuli. Activation of critical enzymes by kinase phosphorylation alone is not enough to provide adequate regulation

Prices direct from United States Biological

Quick response times

Exclusive Biosave savings/discounts

SPECIFICATIONS

Catalog Number

P9109-14Z2-AP

Size

200ul

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum, Mouse

Form

Supplied as a liquid in PBS, pH 7.2. Contains ~0.09% sodium azide. Conjugated to Alkaline Phosphatase.

P Type

Pab

Purity

Purified by Protein G affinity chromatography.

Isotype

IgG

References

1.Deloukas, P., et al., Nature 414(6866):865-871 (2001). 2.Kaplan, R., et al., Proc. Natl. Acad. Sci. USA 87(18):7000-7004 (1990). 3.Krueger, N.X., et al., EMBO J. 9(10):3241-3252 (1990). 4.Sap, J., et al., Proc. Natl. Acad. Sci. USA 87(16):6112-6116 (1990). 5.Jirik, F.R., et al., FEBS Lett. 273(1-2), 239-242 (1990).

Additional Info

Recognizes human PTPalpha. Species Crossreactivity: mouse.