RAB35 pAb

The Ras-related superfamily of guanine nucleotide binding proteins includes the R-Ras, Rap, Ral/Rec and Rho/Rab subfamilies, all of which are thought to play an important role in either endocytosis or in biosynthetic protein transport. The process of transporting newly synthesized proteins from the endoplasmic reticulum (ER) to various stacks of the Golgi complex and to secretory vesicles involves the movement of carrier vesicles and requires Rab protein function. Rab 35, also known as Rab 1C or RAY, is a 201 amino acid lipidanchored protein that is thought to function as a GTPase, playing a role in exocytotic and endocytotic pathways and functioning as an important factor in cytokinesis. Rab 35 is expressed ubiquitously and is encoded by a gene that maps to human chromosome 12, which houses over 1,100 genes and comprises approximately 4.5% of the human genome.

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SPECIFICATIONS

Catalog Number

BS5877

Size

100ug/100ul

Applications

WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Form

liquid

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Antigen

Synthetic peptide, corresponding to amino acids 146-191 of Human RAB35.

Species

RAB35 pAb detects endogenous levels of RAB35 protein.

Dilutions

WB: 1:500~1:1000

Swiss Prot

Q15286

Storage Temp

Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.

Concentration

1ug/ul