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RAB38 pAb

RAB38 pAb

Cat no: BS5878

Supplier: Bioworld Technology, Inc.
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The Ras-related superfamily of guanine nucleotide binding proteins includes the R-Ras, Rap, Ral/Rec and Rho/Rab subfamilies. Increasing data suggests an important role for Rab proteins in either endocytosis or in biosynthetic protein transport. The process of transporting newly synthesized proteins from the endoplasmic reticulum to various stacks of the Golgi complex and to secretory vesicles involves the movement of carrier vesicles and requires Rab protein function. Rab proteins are also an integral part of endocytic pathways. Rab 38, also known as rrGTPbp or NY-MEL-1, is a melanocyte- and lung-specific member of the Rab family of proteins and localizes to the cell membrane, where it is believed to participate in melanosomal transport and docking. Rab 38 may play an important role in melanogenesis and in the targeting of TRP1, a protein involved in the production of melanin. A mutation in the gene encoding Rab 38 may result in oculocutaneous albinism (OCA), a condition in which pigment is absent from eye, skin and hair.
Catalogue number: BS5878
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Western Blot
Size: 100ug/100ul
Swiss prot: P57729
Dilutions: WB: 1:500~1:1000
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 122-167 of Human RAB38.
Species: RAB38 pAb detects endogenous levels of RAB38 protein.
Molecular weight: ~ 24 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Ras-related protein Rab-38; Melanoma antigen NY-MEL-1; RAB 38
Additional info: For research use only, not for use in diagnostic procedure.

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