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Rad GTPase (L80) Peptide

Cat no: BS3133P

Rad GTPase (L80) Peptide

The Ras-encoded family of proteins bind GDP and GTP with high affinity. They possess a low level of intrinsic GTPase activity that increases more than 100-fold when interacting with cytosolic GTPase activating protein (GAP). Ras family members include H-Ras, K-Ras, N-Ras, M-Ras, R-Ras, ERas, Rheb, TC 21, RASL11B and Rad (Ras associated with diabetes) GTPase.Rad GTPase is a GTP-binding protein that is similar to Ras but has unique features. Unlike other small GTPases, Rad GTPase lacks typical pren-ylation motifs at its C terminus. The Rad GTPase enzyme binds calmodulin, inhibits vascular lesion formation, has low intrinsic GTPase activity and cannot be stimulated by any known GAP molecules. Rad GTPase is expressed in skeletal muscle, cardiac muscle and lung tissues and is overexpressed in the skeletal muscle tissue of individuals with type II diabetes.

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SPECIFICATIONS

Catalog Number

BS3133P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide Rad GTPase (L80). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

P55042

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS3133 Rad GTPase (L80) pAb.

Alternative Names

GTP-binding protein RAD; RAD1; Ras associated with diabetes; RRAD; RAD

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