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Rad51D (A152) Peptide

Rad51D (A152) Peptide

Cat no: BS2691P

Supplier: Bioworld Technology, Inc.
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Rad52 family members (Rad50, Rad51B/C/D, Rad52, Rad54, MRE11) mediate DNA double-strand break repair (DSBR) for DNA damage that otherwise could cause cell death, mutation or neoplastic transformation. Rad51 (RECA, BRCC5) interacts with BRCA1 and BRCA2 to influence subcellular localization and cellular response to DNA damage. BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis from deregulation of Rad51. Rad52 forms a heptameric ring that binds single-stranded DNA ends and catalyzes DNA-DNA interaction necessary for the annealing of complementary strands. Rad52 can interact with Rad51. Rad54A of the DEAD-like helicase superfamily binds to double-strand DNA and induces a DNA topological change, which is thought to facilitate homologous DNA pairing and stimulate DNA recombination. Rad54B of the DEAD-like helicase superfamily binds to double-stranded DNA and displays ATPase activity in the presence of DNA. Rad54B is abundant in testis and spleen, and mutations of this gene occur in primary lymphoma and colon cancer
Catalogue number: BS2691P
Applications: Block/Neutralize/Inhibit
Swiss prot: O75771
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide Rad51D (A152). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: RAD51; BRCC5; HRAD51; HSRAD51; HST16930; RAD51A; RAD51D; RAD51L3; RECA
Additional info: This peptide can be used with studies using BS2691 Rad51D (A152) pAb.

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