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Rad52 (N99) Peptide

Cat no: BS1691P

Rad52 (N99) Peptide

DNA double-strand breaks are generated by ionizing radiation and endogenously produced radicals, and they often are repaired through the RAD52 homologous recombination pathway. The RAD52 family includes RAD51, RAD52, RAD54, RAD54B and MRE11 genes. Rad51 and Rad52 proteins perform the key steps in homologous recombination (HR), including the search for DNA homology and strand exchange, through similar mechanisms. Mre11 functions in both non-homologous end joining, and meiotic HR, and it is essential in mitosis for chromosome maintenance. Rad54 belongs to the SWI2/SNF2 subfamily of ATPases, which includes the DNA helicases involved in replication, recombination, and repair, as it contains seven amino acid sequence motifs that are largely conserved.

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SPECIFICATIONS

Catalog Number

BS1691P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide Rad52 (N99). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

P43351

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS1691 Rad52 (N99) pAb.

Alternative Names

DNA repair protein RAD52 homolog; RAD52

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