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Raf-B mAb

Raf-B mAb

Cat no: MB0117

Supplier: Bioworld Technology, Inc.
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Raf-1 is a cytoplasmic protein with intrinsic serine/threonine activity. It is broadly expressed in nearly all cell lines tested to date and is the cellular homolog of v-Raf, the product of the transforming gene of the 3611 strain of murine sarcoma virus. The unregulated kinase activity of the v-Raf protein has been associated with transformation and mitogenesis while the activity of Raf-1 is normally suppressed by a regulatory N-terminal domain. Raf-A, a second member of the Raf gene family of serine/threonine protein kinases, exhibits substantial homology to Raf-1 within the kinase domain of the two molecules, but less homology elsewhere. Expression of Raf-B is highly restricted with highest levels in the cerebrum and testis.
Catalogue number: MB0117
Reactivities: Human, Mouse
Hosts: Mouse
Applications: Western Blot
Size: 100ug/100ul
Swiss prot: P15056
Dilutions: WB:1:300~1000
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Recombinant full length Human Raf-B.
Species: Raf-B mAb detects endogenous levels of Raf-B protein.
Molecular weight: Predicted band size:86KDa Observed band size:95KDa
Purity: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: 94 kDa B raf protein; B raf 1; B Raf proto oncogene serine threonine protein kinase; BRAF1; BRAF; BRAF; BRAF1; cRmil; FLJ95109; MGC126806; MGC138284; Murine sarcoma viral (v-raf) oncogene homolog B1; Murine sarcoma viral v raf oncogene homolog B1; Proto-oncogene B-Raf; Proto-oncogene c-Rmil; RAFB 1; RAFB1; Serine/threonine-protein kinase B-raf; v raf murine sarcoma viral oncogene homolog B1; v-Raf murine sarcoma viral oncogene homolog B1; NS7; BRAF1; RAFB1; B-RAF1
Additional info: For research use only, not for use in diagnostic procedure.

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