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RAI3 (L179) pAb

RAI3 (L179) pAb

Cat no: BS3199

Supplier: Bioworld Technology, Inc.
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Retinoic acid-induced protein 3 (RAI3) is a transmembrane G protein-coupled receptor that affects many essential biological processes including embryogenesis,cell growth, differentiation and apoptosis. RAI3 may also be involved in maintaining homeostasis of epithelial cells. Retinoic acid receptors directly regulate RAI3 during its transcription in embryonal carcinoma differentiation. RAI3 expression is upregulated in most tumor cell lines that express mutant p53, suggesting that p53 interacts with the promoter of RAI3 and represses its expression at the beginning of apoptosis. RAI3 is a potential molecular target for diagnosing breast cancer; selective suppression of signals from RAI3 may have a place in breast cancer treatments.
Catalogue number: BS3199
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Western Blot
Size: 100ug/100ul
Swiss prot: Q8NFJ5
Dilutions: WB: 1:500~1:1000
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 150-200 of Human RAI3.
Species: RAI3 (L179) pAb detects endogenous levels of RAI3 protein.
Molecular weight: ~42 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Retinoic acid-induced gene 1 protein; RAIG-1; Orphan G-protein coupling receptor PEIG-1; GPRC5A; RAI3; RAIG1
Additional info: For research use only, not for use in diagnostic procedure.

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