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RANKL (A72) Peptide

RANKL (A72) Peptide

Cat no: BS1867P

Supplier: Bioworld Technology, Inc.
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Members of the tumor necrosis factor (TNF) receptor superfamily interact with signaling molecules of the TNF receptor-associated factor (TRAF) family to activate the NFkB and JNK pathways. RANK (receptor activator of NFkB) is a member of the TNFR family identified on dendritic cells. This type I membrane receptor is expressed in a broad range of tissues. The C-terminus of RANK is required for RANK to bind TRAF2, 5 and 6, and it is also necessary for stimulating NFkB activation. The ligand for this receptor, RANKL (also designated TRANCE, OPGL or ODF), is a type II transmembrane protein expressed primarily in lymphoid tissues and T cell lines. RANKL appears to be an important regulator of T cells and osteoclasts.
Catalogue number: BS1867P
Applications: Block/Neutralize/Inhibit
Swiss prot: O14788
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide RANKL (A72). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: RANK Ligand; OPGL; ODF; TRANCE
Additional info: This peptide can be used with studies using BS1867 RANKL (A72) pAb.

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