RANTES (Regulated on Activation Normal T-cell Expressed and Secreted, Regulated Upon Activation Normally T Expressed and Presumably Secreted, Beta Chemokine RANTES Precursor, CCL5, Chemokine (C-C Motif) Ligand 5, Chemokine CC Motif Ligand 5, D17S136E, MGC

Applications: \nSuitable for use in ELISA and Western Blot. Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nCellular Localization: Secreted\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degrees C. Aliquots are stable for at least 3 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

R1100-15B

Size

100ug

Applications

ELISA, WB

Hosts

Rat

Reactivities

Hum, Mouse

Form

Supplied as a liquid in PBS, pH 7.2. No preservative added.

P Type

Mab

Purity

Purified by Protein G affinity chromatography.

Isotype

IgG2a

References

Bleul CC et al. The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry. Nature 382:829-33 (1996). <PUBMED:8752280>Tashiro K et al. Signal sequence trap: a cloning strategy for secreted proteins and type I membrane proteins. Science 261:600-3 (1993). <PUBMED:8342023>Schall TJ et al. Molecular cloning and expression of the murine RANTES cytokine: structural and functional conservation between mouse and man. Eur J Immunol 22:1477-81 (1992). <PUBMED:1376260>Schall TJ et al. Selective attraction of monocytes and T lymphocytes of the memory phenotype by cytokine RANTES. Nature 347:669-71 (1990). <PUBMED:1699135>

Additional Info

Species Crossreactivity: Crossreacts with Human and Mouse. Not yet tested in other species.