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RARbeta (L359) Peptide

Cat no: BS1315P

RARbeta (L359) Peptide

Retinoids are metabolites of vitamin A (retinol) that are important signaling molecules during vertebrate development and tissue differentiation. Retinoic acid receptors (RARs) and retinoid X receptors (RXRs) are nuclear transcription factors that modulate the effects of retinoids (RA) on gene expression. Most retinoid forms (including all trans RA, 9-cis RA, 4oxo RA and 3,4 dihydro RA) activate RAR family members, whereas RXR family members are activated by 9-cis-RA only. RA binds RARs, inducing a change in receptor configuration that allows DNA binding and increased gene transcription from specific genes to occur. RAR family members, which include RARalpha, RARbeta and RARgamma , belong to the same class of nuclear transcription factors as thyroid hormone receptors, vitamin D3 receptor and ecdysone receptor. Retinoid receptor expression is tissue specific; the skin expresses RARgamma and RXRalpha.

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SPECIFICATIONS

Catalog Number

BS1315P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide RARbeta (L359). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

P10826

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS1315 RARbeta (L359) pAb.

Alternative Names

RARB; HAP; NR1B2; RAR-BETA; RAR-EPSILON; RRB2

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