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RASSF2 Peptide

Cat no: BS5884P

RASSF2 Peptide

Ras is a small GTP-binding protein involved in many cellular processes, including proliferation, differentiation and apoptosis. Ras transmits signals of cell surface receptors by binding to a variety of effector molecules. In addition to the well-characterized effectors Raf and PI-3 kinase, Ras also interacts with a group of homologous, noncatalytic proteins composed of RASSF1, RASSF2, RASSF3, AD037 and Nore1. RASSF1 is a potential tumor suppressor gene that plays an important role in tumor pathogenesis. Nore1 binds to Ras in response to EGF or serum stimulation, but its function has yet to be determined. RASSF2 is a nuclear protein containing a Ras-associating domain and a SARAH domain. RASSF2 isoform A is inactivated in colorectal cancer cells by CpG island promoter hypermethylation.

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SPECIFICATIONS

Catalog Number

BS5884P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide RASSF2. (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

P50749

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS5884 RASSF2 pAb.

Alternative Names

Ras association domain-containing protein 2; KIAA0168

SUPPLIER INFO

Bioworld Technology, Inc.

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