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Rb (P789) Peptide

Rb (P789) Peptide

Cat no: BS1311P

Supplier: Bioworld Technology, Inc.
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The retinoblastoma tumor suppressor gene product, known as Rb or pRb, regulates differentiation, apoptosis and cell cycle control by coordinating the cell cycle, at G1/S, with transcriptional machinery that includes the heterodimeric E2F family. During G1, cyclin D (D1, 2, 3)-dependent kinase-mediated phosphorylation of Rb at Ser 795 marks the conversion of Rb from a transcriptionally repressive, hypophosphorylated state to an inactive, phosphorylated state, which may be sustained through mitosis by differential phosphorylation of up to 16 putative serine or threonine residues, including Ser 249/Thr 252, Thr 373, Thr 356, Ser 780, Ser 807/Ser 811 and Thr 821/Thr 826.
Catalogue number: BS1311P
Applications: Block/Neutralize/Inhibit
Swiss prot: P06400
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide Rb (P789). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: RB1; OSRC; P105-RB; PP110; RB
Additional info: This peptide can be used with studies using BS1311 Rb (P789) pAb.

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