RFX3 pAb

The EP element is bound by an ubiquitous nuclear protein complex that consists of homo- and heterodimers involving the RFX1, RFX2 and RFX3 proteins. The RFX proteins represent an essential class II transcription factor family that shares several conserved regions, including the centrally located DNA-binding domain (DBD) and the D region found in the C-terminal part of these proteins which facilitates dimerization. RFX complexes can activate the enhancer elements of several HBV genes and also promote the induction of MHC class II genes in response to interferon-g stimulation. Two additional subunits, RFX5, RFX-B/Ank, are also involved in the RFX complexes, yet they bind additional elements in the X1 half of the X box.

Prices direct from Bioworld Technology, Inc.

Quick response times

Exclusive Biosave savings/discounts

SPECIFICATIONS

Catalog Number

BS5893

Size

100ug/100ul

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Form

liquid

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Antigen

Synthetic peptide, corresponding to amino acids 694-739 of Human RFX3.

Species

RFX3 pAb detects endogenous levels of RFX3 protein.

Dilutions

WB: 1:500~1:1000\nIHC: 1:50~1:200

Swiss Prot

P48380

Storage Temp

Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.

Concentration

1ug/ul