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RGS1 pAb

RGS1 pAb

Cat no: BS5894

Supplier: Bioworld Technology, Inc.
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Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors. In mammals, G protein (alpha), (beta) and (gamma) polypeptides are encoded by at least 16, 4 and 7 genes, respectively. Most interest in G proteins has been focused on their (alpha) subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Several G(alpha) GTPase activating proteins (GAPs) have been identified and are designated RGS1, RGS2, RGS4, RGS7, RGS9, RGS10 and GAIP (G(alpha)-interacting protein). Each of these proteins has been shown to deactivate specific G(alpha) isoforms by increasing the rate at which they convert GTP to GDP. RGS2 has been shown to be an inhibitor of G(alpha) q function. RGS9 expression is restricted to photoreceptor cells and RGS9 has been shown to regulate G(alpha) t.
Catalogue number: BS5894
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: Q08116
Dilutions: WB: 1:500~1:1000 IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 161-206 of Human RGS1.
Species: RGS1 pAb detects endogenous levels of RGS1 protein.
Molecular weight: ~ 22 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Regulator of G-protein signaling 1; RGS-1; B-cell activation protein BL34; Early response protein 1R20; 1R20; BL34; IER1
Additional info: For research use only, not for use in diagnostic procedure.

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