RGS10 Peptide

Cat no: BS5895P

Supplier: Bioworld Technology, Inc.

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Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors. In mammals, G protein alpha, beta and gamma polypeptides are encoded by at least 16, 4 and 7 genes, respectively. Most interest in G proteins has been focused on their alpha subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Four Galpha GTPase-activating proteins (GAPs) have been identified and are designated RGS1 (regulator of G protein signaling), RGS4, RGS10 and GAIP (Galpha-interacting protein). Each of these proteins has been shown to deactivate specific Galpha isoforms by increasing the rate at which they convert GTP to GDP. RGS1, RGS4 and GAIP bind tightly to and exhibit GAP activity towards Galpha i, Galpha o and Galpha t, but not Galpha s. RGS10 increases the GTP hydrolytic activity of several members of the Galpha i sub-family, including Galpha i-3, Galpha z and Galpha o.

Catalogue number:	BS5895P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	O43665
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide RGS10. (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	Regulator of G-protein signaling 10
Additional info:	This peptide can be used with studies using BS5895 RGS10 pAb.

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RGS10 Peptide

Cat no: BS5895P

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