RGS2 pAb

Cat no: BS6724

Supplier: Bioworld Technology, Inc.

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Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors. In mammals, G protein a, b and g polypeptides are encoded by at least 16, 4 and 7 genes, respectively. Most interest in G proteins has been focused on their a subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Several Ga GTP-ase activating proteins (GAPs) have been identified and are designated RGS1, RGS2, RGS4, RGS7, RGS9, RGS10 and GAIP (G(alpha)-interacting protein). Each of these proteins has been shown to deactivate specific G(alpha) isoforms by increasing the rate at which they convert GTP to GDP. RGS2 has been shown to be an inhibitor of G(alpha)q function. RGS9 expression is restricted to photoreceptor cells and RGS9 has been shown to regulate G(alpha)t.

Catalogue number:	BS6724
Reactivities:	Human, Mouse, Rat
Hosts:	Rabbit
Applications:	Immunohistochemistry, Western Blot
Size:	100ug/100ul
Swiss prot:	P41220
Dilutions:	WB: 1:500~1:2000 IHC: 1:50~1:200
Form:	liquid
Storage buffer:	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration:	1ug/ul
Antigen:	Recombinant full length Human RGS2.
Species:	RGS2 pAb detects endogenous levels of RGS2 protein.
Molecular weight:	~ 24 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp:	Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names:	Basic helix-loop-helix phosphoprotein G0S8; Cell growth inhibiting protein 31; Cell growth-inhibiting gene 31 protein; G0 to G1 switch regulatory 8 24; G0/G1 switch regulatory protein 8; GOS8; OTTHUMP00000060765; Regulator of G protein signaling 2; Regulator of G protein signalling 2 24; Regulator of G-protein signaling 2; Regulators of G protein signaling XRGSVI; RGS 2; RGS2; RGS2; RGS2;
Additional info:	For research use only, not for use in diagnostic procedure.

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RGS2 pAb

Cat no: BS6724

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